EYE HEALTH SPECIAL REPORT
Age-Related Macular Degeneration (AMD) is a leading cause of blindness worldwide with limited pharmaceutical and surgical treatment options. In the United States, more than 50% of all blindness is caused by AMD. Other risk factors for AMD include high blood pressure, cardiovascular disease, obesity, smoking, and a diet high in fats and low in green leafy vegetables and fish. Nutraceuticals are now offering scientific evidence that show a slowing down, and even possible reversing, of AMD.
AREDS - EYE HEALTH
In 1992 The Age-Related Eye Disease Study (AREDS) was designed to determine if daily intake of certain vitamins and minerals could reduce the risk of cataract and advanced age-related macular degeneration (AMD).
The study used a combination of vitamins E and C, beta-carotene, and zinc and is now known as the AREDS formulation.
Results: 25 percent reduction over a five-year period!
AREDS - 2
In 2006, the investigators began a separate clinical trial called AREDS2. The modifications I the original formula resulted in added lutein and zeaxanthin (found in Shaklee Caratomax), Omegas; DHA and EPA (Shaklee OmegaGuard), a reduction of beta-carotene and zinc.
Results: In the AREDS2 trial, lutein/zeaxanthin appeared to have some benefits for reducing the risk of developing advanced AMD!
Chew et al. "Long-Term Effects of Vitamins C, E, Beta-Carotene and Zinc on Age-Related Macular Degeneration." Ophthalmology, published online April 11, 2013.
AREDS2 Research Group. "Lutein/Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration. The Age-Related Eye Disease Study 2 (AREDS2) Controlled Randomized Clinical Trial." JAMA, published online May 5, 2013.
AREDS2 Research Group. "Lutein/Zeaxanthin for the Treatment of Age-Related Cataract." JAMA Ophthalmology, published online May 5, 2013.
Shaklee Study Resource Link
Health Science Articles
AGE-RELATED MACULAR DEGENERATION PREVENTION
Implications for preventing advanced AMD
The AREDS formulation is the only treatment known to reduce the risk of advanced AMD. The AREDS follow-up study found that taking the AREDS formulation has a persistent benefit for reducing the risk of advanced AMD.
Source: National Eye Institute - Department of Health and Human Services | The National Institutes of Health | USA.gov
Lutein and zeaxanthin supplementation and association with visual function in age-related macular degeneration.
PubMed link Shaklee products
BREAKING NEWS: VIVIX CASE STUDY
Case Study: Effect of the combination of AREDS2 formulation and a polyphenol preparation (Vivix) on dry age-related macular degeneration: analysis of case studies
Analysis of a series of case studies suggests that Vivix may play a role in supporting retinal health.
AMD patients supplemented with the standard nutritional intervention, the AREDS2 formula (4), simultaneously received Vivix (1 tsp per day) for four months resulted in structural and/or visual improvements in approximately 70% of patients with macular degeneration.
Results: Approximately 70% of these patients experienced improvements, including gains in visual acuity, reductions in soft drusen, and/or improvements in anatomical structure.
Actual Study: Print out for your Doctor
1Robert T. McHugh, O.D., 2 Jack L. Hollins, M.D., 3Francis C. Lau, Ph.D. and 3Bruce P. Daggy, Ph.D. 1McHugh Optometry, Morehead, KY; 2Hollins Ophthalmology, Lexington, KY; 3 Shaklee Research Center, Pleasanton, CA
These intriguing observations, not yet confirmed by randomized controlled studies, do not distinguish between the possibilities that the effects of Vivix on retinal function depend on synergistic interactions with the AREDS2 formula, or if Vivix alone is responsible.
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